Journées MAS de la SMAI
Modélisation et Statistiques des Réseaux
Rennes, 27-29 août 2008

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Jean-Philippe VERT


Inference of missing edges in biological networks


The elucidation of large-scale biological networks is currently a major challenge in systems biology. These networks include, for example, protein-protein interaction, metabolic, or regulatory networks, which describe various aspects of how life is organized at the molecular level. While these large-scale networks are slowly being discovered using various technologies, in silico methods to expand our current knowledge and predict missing edges are needed. In this talk I will present some approaches we developed in the last few years to infer missing edges using supervised machine learning techniques, and illustrate their behaviour on several examples.
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